Sasha Alexander left NCIS because of the grueling and demanding filming schedule, which was physically and mentally exhausting for her. She felt she couldn't handle the long working hours, which often spanned 17 hours a day for about 10 and a half months a year, and she wanted a better work-life balance. The show's intensive production pace left her feeling burnt out, leading to her decision to leave after two seasons. NCIS co-creator Donald P. Bellisario confirmed that Alexander came to him with tears, saying she "just can't work this hard," and he supported her decision to step away rather than force her to continue under such conditions. Alexander has expressed no regrets for leaving, as it allowed her to focus on family and other creative pursuits.