Short answer: Allegra (fexofenadine) is not clearly established as safe in pregnancy, and most guidelines prefer other options, so consult your prenatal care team before using it. Details

• Summary of guidance: Many healthcare sources indicate that while some antihistamines (like cetirizine and loratadine) have more safety data in pregnancy, the data for fexofenadine (Allegra) are limited, so it is generally not a first-line choice during pregnancy. If allergy symptoms are manageable with safer options, those are typically recommended first, and any use of Allegra should be under medical supervision. Safety classifications can vary by country and over time as new studies emerge.

• What this means for you: If you’re pregnant and considering Allegra, discuss with your obstetrician or a maternal-fetal medicine specialist. They can weigh the potential benefits for your symptoms against any uncertain risks to you and the baby, and may suggest alternatives such as intranasal therapies or other antihistamines with stronger safety data in pregnancy.

What to talk to your clinician about

• Your allergy symptoms (seasonal vs. chronic, severity, impact on sleep and daily activities).
• Other safe options to try first (e.g., intranasal corticosteroids like budesonide, or antihistamines with more pregnancy safety data).
• Potential risks and benefits of starting Allegra during pregnancy in your specific case.
• Any other medications, supplements, or conditions that might interact with allergy treatments.

If you’d like, I can summarize current recommendations from specific guidelines (e.g., ACOG, NHS) or help you compare Allegra with safer alternatives during pregnancy.