It is generally not recommended to drink alcohol while taking Lexapro (escitalopram). Drinking alcohol can increase the risk of side effects such as drowsiness, dizziness, and worsened depression or anxiety symptoms. Alcohol may also reduce the effectiveness of Lexapro in treating these conditions. Some doctors might allow moderate alcohol consumption in certain cases, but this should only be done with a doctor's approval and careful monitoring. Overall, avoiding alcohol while on Lexapro is the safest choice to prevent potentially serious interactions and complications.