The pronunciation of Worcestershire sauce is often tricky because it doesn't sound like it's spelled. The most common and widely accepted pronunciation in English is: "WUSS-ter-sheer"
(or sometimes "WUSS-ter-sheer sauce") Here’s a breakdown:

• Worcester is pronounced like "WUSS-ter"
• shire is pronounced like "sheer"

So, putting it together: WUSS-ter-sheer sauce. This is the typical British English pronunciation, and it’s also commonly used in American English.