The distance from Miami to Key West is approximately 159 to 166 miles (256 to 267 kilometers), depending on the source. The drive typically takes about 4 hours without stops along the scenic Overseas Highway, which connects the islands with a series of bridges including the famous Seven Mile Bridge

. This route offers spectacular views of the ocean and several charming stops such as Key Largo, Islamorada, and Marathon, making the journey a memorable road trip experience

. Traffic can be busy at times since the highway is mostly two lanes

. In summary:

• Distance: About 159-166 miles (256-267 km)
• Driving time: Around 4 hours nonstop
• Route: Overseas Highway (US Route 1)
• Notable stops: Key Largo, Islamorada, Marathon, Seven Mile Bridge

This drive is considered one of the most beautiful in the U.S. and is well worth the time for the views and attractions along the way