Synthetics can refer to two different things: synthetic drugs and synthetic fibers.

Synthetic drugs are created using man-made chemicals rather than natural ingredients. They aim to mimic the effects of existing illicit drugs, such as cannabis, cocaine, and ecstasy. Synthetic drugs are also known as "new psychoactive substances" (NSPs) . Examples of synthetic drugs include Ecstasy, LSD, and methamphetamine. Synthetic drugs are often marketed as "legal," safe, and acceptable alternatives to illicit drugs, but this does not mean that they are legal or safe. Synthetic drugs have different chemical structures from the illicit substances they are trying to mimic, and manufacturers of synthetic drugs constantly change their chemical structures to try and stay ahead of the law. Due to the constantly growing number of chemicals that are developed, designer drug users have no way of knowing what the drugs they take might contain. Synthetic drugs can be very dangerous, and there is limited research on the short- and long-term effects of these substances.

Synthetic fibers, on the other hand, are fibers made through chemical processes. The compounds used to make synthetic fibers come from fossil-based resources, including petroleum-based chemicals and petrochemicals. Synthetic fibers have different properties from natural fibers and are often stretchier, more waterproof, and more stain-resistant, making them highly consumer-friendly. Examples of synthetic fibers include polyester and nylon. Synthetic fibers currently represent 64% of global fiber production volumes.

In summary, synthetics can refer to synthetic drugs, which are man-made chemicals that aim to mimic the effects of existing illicit drugs, or synthetic fibers, which are fibers made through chemical processes.