OxyContin is a trade name for the narcotic oxycodone hydrochloride, which is a prescription pain medication and an opioid drug synthesized from thebaine, an alkaloid found in opium. Oxycodone is a semi-synthetic narcotic analgesic and is marketed alone as OxyContin® in 10, 20, 40, and 80 mg extended-release tablets and other immediate-release capsules like 5 mg OxyIR®. It is also marketed in combination products with aspirin such as Percodan® or acetaminophen such as Roxicet®. Oxycodone has a high abuse potential and is prescribed for moderate to high pain relief associated with injuries, bursitis, dislocation, fractures, neuralgia, arthritis, and lower back and cancer pain. It is also used postoperatively and for pain relief after childbirth.

In summary, OxyContin is made of oxycodone hydrochloride, which is synthesized from thebaine, an alkaloid found in opium.