The derivative of 2x is 2. The power rule of differentiation states that the derivative of x to the power n is given by n times x to the power n minus 1, that is, d(x^n)/dx = n x^(n-1). We can also use the derivative rule of scalar multiple of a function, that is, d(kf(x))/dx = k d(f(x))/dx. Therefore, we have d(2x)/dx = 2 dx/dx = 2. Hence, the differentiation of 2x is equal to 2.