Here are some things you should not do if you have pleurisy:

• Do not smoke: Smoking can make pleurisy worse and can also lead to other lung problems.

• Do not take two or more pain medicines together: Over-the-counter pain medicines, such as acetaminophen (Tylenol), ibuprofen (Advil, Motrin), or naproxen (Aleve), can help relieve pain caused by pleurisy. However, do not take two or more pain medicines together.

• Do not give aspirin to anyone younger than 20: Aspirin should not be given to anyone younger than 20 because of the risk of Reye syndrome.

• Do not ignore changes in your health: Watch closely for changes in your health, and be sure to contact your doctor or nurse advice line if you experience any worsening symptoms or have concerns.

It is important to follow the treatment plan recommended by your healthcare provider, which may include taking medications, getting rest, and avoiding activities that worsen your symptoms. If you have pleural effusion, your doctor may need to drain the fluid from your pleura. Treatment for pleurisy depends on the underlying cause, and early diagnosis and treatment can help you feel better.