Izzie Stevens from Grey's Anatomy did not die. She was diagnosed with stage 4 metastatic melanoma in season 5, but after treatment, she became cancer-free. She married Alex Karev and eventually left Seattle to start a new life after their divorce, not returning to the hospital. Her character is alive and was later revealed in season 16 to be raising twins with Alex in Kansas while working as a surgical oncologist. The decision not to kill her character was partly to leave an opportunity for the actress to return, which never happened.