Tylenol Extra Strength can be taken as 2 tablets every 6 hours while symptoms last. The maximum dose should not exceed 6 tablets in 24 hours unless directed by a doctor. Each tablet contains 500 mg of acetaminophen, so the maximum daily dose is 3,000 mg for this specific version, which is slightly more conservative than the general 4,000 mg acetaminophen limit due to safety considerations. It is important to follow these guidelines and consult with a healthcare provider especially if there are liver concerns or other health conditions.