Buffalo Bill can refer to different things, depending on the context. Here are some possible meanings:

• Buffalo Bills: The Buffalo Bills are a professional American football team based in the Buffalo-Niagara Falls metropolitan area. The team is named after William Frederick Cody, also known as Buffalo Bill, who was an American soldier, bison hunter, and showman.

• William Frederick Cody: William Frederick Cody, also known as Buffalo Bill, was an American soldier, bison hunter, and showman. He was born in Le Claire, Iowa Territory (now the U.S. state of Iowa), but he lived for several years in his fathers hometown in modern-day Mississauga, Ontario, Canada, before the family returned to the Midwest and settled in the Kansas Territory. He received a medal of honor in 1972, and it is his name by which Buffalos football team is named.

• Buffalo Bill (character): Buffalo Bill is also the name of a fictional character in the novel and movie "The Silence of the Lambs". In the story, Buffalo Bill is a serial killer who murders overweight women and skins them so he can make a "woman suit" for himself. The character is not related to William Frederick Cody or the Buffalo Bills football team).

In summary, Buffalo Bill can refer to a football team, a historical figure, or a fictional character, depending on the context.